605629-49-0

Basic information

• Product Name: 4-benzylamino-1H-pyrrole-2-carboxylic acid benzyl ester
• Synonyms: 4-benzylamino-1H-pyrrole-2-carboxylic acid benzyl ester
• CAS NO: 605629-49-0
• Molecular Weight: 306.364
• Mol File: 605629-49-0.mol

Chemical Properties

• CAS DataBase Reference: 4-benzylamino-1H-pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzylamino-1H-pyrrole-2-carboxylic acid benzyl ester(605629-49-0)
• EPA Substance Registry System: 4-benzylamino-1H-pyrrole-2-carboxylic acid benzyl ester(605629-49-0)

Safety Data

• Hazardous Substances Data: 605629-49-0(Hazardous Substances Data)

Upstream product

• 163594-14-7 (2S)-4-oxo-N-(9-phenylfluoren-9-yl)proline benzyl ester 
• 100-46-9 benzylamine 

Downstream Products

• 1010830-53-1 benzyl 4-(1-benzylureido)-1H-pyrrole-2-carboxylate 
• 1010830-52-0 benzyl 4-(1-benzyl-3((R)-1-phenylethyl)ureido)-1H-pyrrole-2-carboxylate 
• 1010830-59-7 benzyl 4-(N-benzylbenzamido)-1H-pyrrole-2-carboxylate 
• 1010830-58-6 C₂₇H₂₄N₂O₄ 
• 1010830-60-0 benzyl 4-(N-benzylphenylsulfonylamido)-1H-pyrrole-2-carboxylate 
• 1010830-51-9 benzyl 4-(1,3-dibenzylureido)-1H-pyrrole-2-carboxylate 
• 605629-63-8 4-[1-benzyl-3-phenyl-3-(2,2,2-trichloroacetyl)ureido]-1H-pyrrole-2-carboxylic acid benzyl ester 
• 605629-62-7 4-[3-allyl-1-benzyl-3-(2,2,2-trichloroacetyl)ureido]-1H-pyrrole-2-carboxylic acid benzyl ester 
• 605629-61-6 4-[1-benzyl-3-ethyl-3-(2,2,2-trichloroacetyl)ureido]-1H-pyrrole-2-carboxylic acid benzyl ester 
• 605629-52-5 4-(3-allyl-1-benzylureido)-1H-pyrrole-2-carboxylic acid benzyl ester 
• 605629-53-6 4-(1-benzyl-3-phenylureido)-1H-pyrrole-2-carboxylic acid benzyl ester 
• 605629-51-4 4-(1-benzyl-3-ethylureido)-1H-pyrrole-2-carboxylic acid benzyl ester 

Relevant articles and documents

2-vinylpyrroles and pyrrolo[3,2-d]pyrimidines from direct addition of aldehydes to 4-amino-pyrrole-2-carboxylate derivatives

A new methodology for the direct preparation of 2-vinylpyrroles is presented. Treatment of 4-amino-pyrrole-2-carboxylates 5a-c and 6a-d with aliphatic aldehydes and TFA furnished 2-vinylpyrroles 2a-k in 9-87% yields. Under similar conditions ureidopyrroles 5a-c reacted with aryl aldehydes to provide pyrrolo[3,2-d]pyrimidines 1a-d in 28-63% yields.

An effective new synthesis of 4-aminopyrrole-2-carboxylates

(Matrix presented) A series of 4-amino-1H-pyrrole-2-carboxylic acid benzyl esters has been synthesized in 61-84% yields on treatment of N-PhF-4-oxoproline benzyl ester and its 3-alkyl-substituted derivatives with different primary and secondary amines and