605674-86-0Relevant articles and documents
Solid-phase synthesis of methyl carboxymycobactin T 7 and analogues as potential antimycobacterial agents
Poreddy, Amruta R.,Schall, Otto F.,Marshall, Garland R.,Ratledge, Colin,Slomczynska, Urszula
, p. 2553 - 2556 (2007/10/03)
A solid-phase approach for the total synthesis of methyl carboxymycobactins 1a-d, with an on-resin cyclization leading to azopine 5 as the key step, was developed. The iron-affinity of these compounds was assessed by a competitive sulfoxine-binding assay, and antimycobacterial activity was tested against the growth of Mycobacterium avium.