60588-53-6 Usage
Uses
Used in Pharmaceutical Research and Development:
N-(3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-phenylacetamide is employed as a research compound for exploring its potential medicinal applications. Its unique structure and properties make it a candidate for the development of new therapeutic agents.
Used in Drug Discovery:
In the field of drug discovery, N-(3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-phenylacetamide is used as a lead compound to identify new drug targets and pathways. Its complex molecular structure allows for the possibility of modulating various biological processes, which could be beneficial in treating certain diseases.
Used in Medicinal Chemistry:
N-(3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-phenylacetamide is utilized in medicinal chemistry as a starting point for the synthesis of new compounds with improved pharmacological properties. Its pyrazole and phenylacetamide components can be modified to create derivatives with enhanced efficacy and selectivity.
Used in Chemical Synthesis:
In the chemical synthesis industry, N-(3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-phenylacetamide serves as an intermediate or building block for the creation of more complex molecules with specific applications in various fields, including materials science and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 60588-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,8 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60588-53:
(7*6)+(6*0)+(5*5)+(4*8)+(3*8)+(2*5)+(1*3)=136
136 % 10 = 6
So 60588-53-6 is a valid CAS Registry Number.
60588-53-6Relevant academic research and scientific papers
Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
Cusan, Claudia,Spalluto, Giampiero,Prato, Maurizio,Adams, Michael,Bodensieck, Antje,Bauer, Rudolf,Tubaro, Aurelia,Bernardi, Paolo,Da Ros, Tatiana
, p. 7 - 13 (2007/10/03)
A new series of potential human 5-LOX inhibitors structurally related to the 1-phenyl-3-pyrazolidinone (phenidone, 2) has been synthesized and the activity against COX-1, COX-2, and human 5-LOX enzymes has been evaluated. In contrast with literature data, we observed that phenidone resulted to be inactive against human 5-LOX, while retains its activity against cyclooxygenases in a micromolar range. The present results suggest that the substitution of the amino function at the 4-position is detrimental in terms of activity toward COX-1 and COX-2, while the presence of a double bond at the 4,5-position does not alter the biological profile against COX. The absence of activity vs. human 5-LOX strongly suggests a re-consideration of phenidone and its analogs as 5-LOX inhibitors in humans.
