60589-39-1Relevant articles and documents
Dual-Reactable Fluorescent Probes for Highly Selective and Sensitive Detection of Biological H2S
Wei, Chao,Wang, Runyu,Zhang, Changyu,Xu, Guoce,Li, Yanyan,Zhang, Qiang-Zhe,Li, Lu-Yuan,Yi, Long,Xi, Zhen
supporting information, p. 1376 - 1381 (2016/05/19)
Hydrogen sulfide (H2S) is an important endogenous signaling molecule with a variety of biological functions. Development of fluorescent probes for highly selective and sensitive detection of H2S is necessary. We show here that dual-reactable fluorescent H2S probes could react with higher selectivity than single-reactable probes. One of the dual-reactable probes gives more than 4000-fold turn-on response when reacting with H2S, the largest response among fluorescent H2S probes reported thus far. In addition, the probe could be used for high-throughput enzymatic assays and for the detection of Cys-induced H2S in cells and in zebrafish. These dual-reactable probes hold potential for highly selective and sensitive detection of H2S in biological systems. Two heads are better than one: Fluorescent probes with two types of reactive heads (R1 and R2) for H2S can lead to a higher selectivity than that of single-reactable probes (See Figure). The probe was used for highly selective and sensitive detection of biological H2S.
Process for preparing 2-hydroxybenzoic aldehydes
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, (2008/06/13)
There is disclosed a catalytic process for preparing, from phenols and formaldehyde 2-hydroxybenzoic aldehydes some of which are new in the art and, more particularly, a high-selectivity process for preparing the aldehydes by direct synthesis from phenols having at least a free ortho position and formaldehyde, in the presence of a catalyst consisting of anhydrous stannous and/or stannic chloride and of an aprotic binder.
