60598-65-4

Basic information

• Product Name: 2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
• Synonyms: CHEMBRDG-BB 5578245;2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE;AKOS BBS-00001253;2-amino-N-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide(SALTDATA: FREE);2-amino-N-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamid
• CAS NO: 60598-65-4
• Molecular Formula: C11H16N2OS
• Molecular Weight: 224.32
• Mol File: 60598-65-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 384.5°C at 760 mmHg
• Flash Point: 186.3°C
• Appearance: /
• Density: 1.213g/cm³
• Vapor Pressure: 4.09E-06mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: 2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE(60598-65-4)
• EPA Substance Registry System: 2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE(60598-65-4)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 60598-65-4(Hazardous Substances Data)

Usage

General Description

2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE is a chemical compound with the molecular formula C13H18N2OS. It is a benzothiophene derivative with an amide group and an aminoethyl substituent. 2-AMINO-N-ETHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE has potential pharmacological effects and is used in research and development of pharmaceuticals. Its precise applications and uses are determined by its specific properties and interactions with biological systems.

InChI:InChI=1/C11H16N2OS/c1-2-13-11(14)9-7-5-3-4-6-8(7)15-10(9)12/h2-6,12H2,1H3,(H,13,14)

Upstream product

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Relevant articles and documents

Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines

Multicomponent Petasis reaction has been widely applied for the synthesis of functionalized amine building blocks and biologically active compounds. Employing primary aromatic amines that are not typical reactive substrates contributes to expand the application scope of the Petasis reaction. In this study, we demonstrated the synthesis of functionalized 2-aminothiophenes using Gewald-reaction-derived 2-aminothiophenes as the amine substrates, whose low reactivity in the Petasis reaction was overcome using hexafluoro-2-propanol as the solvent in a mild condition. The obtained Petasis products are amenable for further transformations owing to the presence of multiple functional handles. A following intramolecular cyclization of selected Petasis products afforded substituted tricyclic heterocycles that incorporate a pharmaceutically interesting thienodiazepine moiety.