60609-82-7Relevant academic research and scientific papers
Preparation of chlorosilyl enolates
Denmark, Scott E.,Stavenger, Robert A.,Winter, Stephen B. D.,Wong, Ken-Tsung,Barsanti, Paul A.
, p. 9517 - 9523 (2007/10/03)
A variety of chlorosilyl enolates has been prepared starting from esters, thiol esters, acylsilanes, and ketones. Two general methods are involved, direct enolsilylation with trichlorosilyl triflate and diisopropylethylamine, and a number of methods based on electrophilic substitution of either C- or O-silyl or stannyl carbonyl compounds. The most useful method is a Hg(OAc)2-catalyzed transsilylation from trimethylsilyl to trichlorosilyl enol ethers, providing a wide range of ketone enolates in good to high yield.
