60611-93-0Relevant academic research and scientific papers
DUTPASE INHIBITORS
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Page/Page column 50, (2008/06/13)
Deoxyuridine derivatives of the formula (I) where R1 is H or various substituents; D is -NHCO-, -CONH-, -0-, -C(=O)-, -CH=CH, -CΞC-, -NR5-; R4 is hydrogen or various substituents; R5 is H, C1-C4 alkyl, C1-C4 alkanoyl; E is Si or C; R6, R7 and R8 are independently selected from C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl or a stable monocyclic, bicyclic or tricyclic ring system; G is -O-, -S-, -CHR10-, -C(=O)-; J is -CH2-, or when G is CHR10 may also be -O- or -NH-; R10 is H, F, -CH3, -CH2NH2, -CH2OH; -OH R11 is H, F, -CH3, -CH2 NH2, -CH2OH, CH(OH)CH3, CH(NH3)CH3; or R10 and R11 together define an olefinic bond, or together form a -CH2-group, thereby defining a cis or trans cyclopropyl group; have utility in the prophylaxis or treatment of protozoal diseases such as malaria.
Sterically Hindered Free Radicals, XIII. Wittig's Radical 4-Benzoyltriphenylmethyl and Analogous Mono-4-substituted Trityl Radicals
Zarkadis, Antonios K.,Neumann, Wilhelm P.,Uzick, Wolfram
, p. 1183 - 1192 (2007/10/02)
The mono-4-R-triphenylmethyl radicals 1, 8b-f, R = tBu, CF3, COMe, COPh, CN, Me, or their quinonoid dimers 4, 9b-f are prepared, most of them for the first time.The degree of dissociation of the latter at 25 deg C is surprisingly high (=/ 33percent, 0.01 M), donors and acceptors being effective here likewise.ESR data are given and discussed.
