606129-49-1 Usage
Description
3-(4-chlorobenzyl)azetidine is an azetidine (A813000) derivative, a class of organic compounds that are structurally similar to amino acids. It features a four-membered nitrogen-containing ring and a 4-chlorobenzyl group attached to the 3-position of the azetidine ring. This unique structure endows it with specific chemical and biological properties, making it a valuable building block in the synthesis of pharmaceuticals and other organic compounds.
Uses
Used in Pharmaceutical Industry:
3-(4-chlorobenzyl)azetidine is used as a key intermediate in the preparation of CCR-3 receptor antagonists. These antagonists are important in the development of drugs targeting chemokine receptors, which play a crucial role in various immune responses and inflammatory processes. By modulating the activity of the CCR-3 receptor, these antagonists can potentially treat a range of conditions, including asthma, allergies, and autoimmune diseases.
Additionally, 3-(4-chlorobenzyl)azetidine is utilized in the synthesis of adenosine nucleoside analogs, which function as A2a receptor agonists. A2a receptors are G protein-coupled receptors that, when activated, can lead to various physiological effects, such as vasodilation, anti-inflammatory actions, and neuroprotection. A2a receptor agonists have potential applications in the treatment of various disorders, including cardiovascular diseases, neurodegenerative conditions, and certain types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 606129-49-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,6,1,2 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 606129-49:
(8*6)+(7*0)+(6*6)+(5*1)+(4*2)+(3*9)+(2*4)+(1*9)=141
141 % 10 = 1
So 606129-49-1 is a valid CAS Registry Number.
606129-49-1Relevant articles and documents
AZETIDINE-SUBSTITUTED PYRAZOLINES AS PAR-1 ANTAGONISTS
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Page/Page column 55, (2008/06/13)
The invention relates to blood clotting, and especially to the use of azetidine-substituted pyrazolines as medicaments, novel azetidine-substituted pyrazolines, methods for the production thereof, and the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases, preferably thromboembolic diseases.
