60632-21-5

Basic information

• Product Name: (E)-2-(4-chlorobenzoyl)but-2-enedioic acid dimethyl ester
• Synonyms: (E)-2-(4-chlorobenzoyl)but-2-enedioic acid dimethyl ester
• CAS NO: 60632-21-5
• Molecular Weight: 282.68
• Mol File: 60632-21-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-chlorobenzoyl)but-2-enedioic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-chlorobenzoyl)but-2-enedioic acid dimethyl ester(60632-21-5)
• EPA Substance Registry System: (E)-2-(4-chlorobenzoyl)but-2-enedioic acid dimethyl ester(60632-21-5)

Safety Data

• Hazardous Substances Data: 60632-21-5(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

Nicotinic acid functionalized organomodified silica as an efficient heterogeneous catalyst for the synthesis of benzoyl fumarate

A new hybrid catalyst has been developed by incorporating nicotinic acid onto an organomodified silica. The catalyst was applied as a heterogeneous catalyst for the synthesis of benzoyl fumarate. The reactions work well in the presence of 20 wt % of the catalyst at room temperature to produce the desired products in high yield. The catalyst could be recovered and reused without appreciable change in activity.

Reactions of Arylaldehydes and N-Sulfonated Imines with Dimethyl Acetylenedicarboxylate Catalyzed by Nitrogen and Phosphine Lewis Bases

(Equation presented) In the reaction of arylaldehydes or N-sulfonated imines (0.5 mmol) with dimethyl acetylenedicarboxylate (DMAD) (0.6 mmol) catalyzed by pyridine or DMAP (20 mol %), we found that (E)-2-aryl-but-2- enedioic acid dimethyl ester 1 or (E)-2-[aryl-(toluene-4-sulfonylimino)methyl]- but-2-enedioic acid dimethyl ester 2 was formed in good yields at 60°C in THF. A plausible mechanism has been proposed.

A new ferrocene-based bulky pyridine as an efficient reusable homogeneous catalyst

An effective approach to reusing a homogeneous catalyst has been demonstrated. A ferrocene-based bulky pyridine has been synthesized and utilized as a homogeneous catalyst for the synthesis of benzoylfumarates as well as for acetylation. After the reaction, the catalyst was separated by simple precipitation and reused without appreciable loss of activity. The Royal Society of Chemistry 2013.