60639-61-4

Basic information

• Product Name: 2-(7-chloro-4-quinolylamino)-N-(1-ethyl-3-piperidyl)benzamide
• Synonyms: 2-(7-chloro-4-quinolylamino)-N-(1-ethyl-3-piperidyl)benzamide
• CAS NO: 60639-61-4
• Molecular Weight: 408.931
• Mol File: 60639-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(7-chloro-4-quinolylamino)-N-(1-ethyl-3-piperidyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(7-chloro-4-quinolylamino)-N-(1-ethyl-3-piperidyl)benzamide(60639-61-4)
• EPA Substance Registry System: 2-(7-chloro-4-quinolylamino)-N-(1-ethyl-3-piperidyl)benzamide(60639-61-4)

Safety Data

• Hazardous Substances Data: 60639-61-4(Hazardous Substances Data)

Upstream product

• 6789-94-2 1-ethylpiperidin-3-amine 

Relevant articles and documents

O-(4-Quinolylamino)benzamides

The disclosure describes new 4-aminoquinoline derivatives of general formula SPC1 And their acid addition salts, where X is a halogen atom or a trifluoromethyl group, Z is a hydrogen atom or a defined substituent, R is group of the formula where A in formula II is a chain of 1 to 5 methylene groups which may be substituted with alkyl, the ring in formula IIIa and IIIb is a piperidine or pyrrolidine ring that may be substituted with alkyl and R1, R2 and R3 represent hydrogen or certain defined substituents. The new 4-aminoquinoline derivatives show anti-malarial activity and, in some cases, show one or more of the following activities:- anti-inflammatory activity, anti-hypertensive activity, anti-trichomonal activity, inhibition of blood platelet aggregation, anti-ulcer activity and activity against allergic asthma. Compounds where --COR is in the o-position with respect to the 7-(halo or trifluoromethyl)-4-quinolylamino group and R is di(lower alkyl)aminopiperidino or --NR10 R11 where R10 is hydrogen or lower alkyl and R11 is di(lower alkyl)amino(lower alkyl) or 1-(lower alkyl)piperidyl show anti-inflammatory activity.