60643-92-7

Basic information

• Product Name: 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide
• Synonyms: 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide;1-(2,4-Dinitrophenyl)-L-Pro-L-Leu-Gly-L-Ile-L-Ala-Gly-L-Arg-NH2
• CAS NO: 60643-92-7
• Molecular Formula: C36H57N13O11
• Molecular Weight: 847.91828
• EINECS: 262-346-0
• Mol File: 60643-92-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.47g/cm³
• Refractive Index: 1.655
• PKA: 13.30±0.46(Predicted)
• CAS DataBase Reference: 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide(60643-92-7)
• EPA Substance Registry System: 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide(60643-92-7)

Safety Data

• Hazardous Substances Data: 60643-92-7(Hazardous Substances Data)

Usage

Description

1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is a synthetic peptide compound derived from the natural hormone vasopressin. It consists of six amino acids and features a dinitrophenyl functional group. 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is utilized in research for studying peptide and protein interactions due to its unique chemical structure and properties, which facilitate the investigation of binding and recognition processes in biological systems.

Uses

Used in Research Applications:
1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is used as a labeling agent for studying peptide and protein interactions. Its chemical structure allows researchers to better understand the binding and recognition processes in biological systems, which can be crucial for developing new therapeutic strategies and understanding the mechanisms of various diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is used as a potential therapeutic agent. Its structural similarity to vasopressin suggests that it may have applications in regulating water balance in the body and could be developed into a drug for treating conditions related to water imbalance, such as diabetes insipidus.
Used in Biochemical Analysis:
1-(2,4-dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is also used in biochemical analysis as a tool for identifying and characterizing specific protein receptors and enzymes. Its unique properties make it a valuable probe for studying the interactions between proteins and their ligands, which can provide insights into the molecular mechanisms underlying various biological processes.

InChI:InChI=1/C36H57N13O11/c1-6-20(4)30(35(56)43-21(5)32(53)41-17-28(50)44-23(31(37)52)9-7-13-40-36(38)39)46-29(51)18-42-33(54)24(15-19(2)3)45-34(55)26-10-8-14-47(26)25-12-11-22(48(57)58)16-27(25)49(59)60/h11-12,16,19-21,23-24,26,30H,6-10,13-15,17-18H2,1-5H3,(H2,37,52)(H,41,53)(H,42,54)(H,43,56)(H,44,50)(H,45,55)(H,46,51)(H4,38,39,40)/t20?,21-,23-,24-,26-,30-/m0/s1