60657-23-0 Usage
Description
Cinobufotenine, also known as bufotenin, is a naturally occurring alkaloid found in various plants and animals, including certain species of toads and mushrooms. It is structurally similar to the neurotransmitter serotonin and has been used in traditional medicine for its psychoactive properties. Cinobufotenine has potential therapeutic effects, including its ability to act as a 5-HT2A receptor agonist, which may have implications for the treatment of certain mental health disorders. However, it is also a regulated substance due to its potential for abuse and toxicity, and its use should only be considered under the guidance of a qualified medical professional.
Uses
Used in Traditional Medicine:
Cinobufotenine is used as a psychoactive substance in traditional medicine for its potential therapeutic effects on mental health disorders.
Used in Pharmaceutical Research:
Cinobufotenine is used as a research compound for its potential therapeutic effects as a 5-HT2A receptor agonist, which may have implications for the treatment of certain mental health disorders.
Used in Drug Regulation:
Cinobufotenine is used as a regulated substance due to its potential for abuse and toxicity, ensuring that its use is considered only under the guidance of a qualified medical professional.
Check Digit Verification of cas no
The CAS Registry Mumber 60657-23-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,5 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60657-23:
(7*6)+(6*0)+(5*6)+(4*5)+(3*7)+(2*2)+(1*3)=120
120 % 10 = 0
So 60657-23-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H18N2O/c1-15(2,3)7-6-10-9-14-13-5-4-11(16)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3/p+1
60657-23-0Relevant articles and documents
Citrus genus plants contain N-methylated tryptamine derivatives and their 5-hydroxylated forms
Servillo, Luigi,Giovane, Alfonso,Balestrieri, Maria Luisa,Casale, Rosario,Cautela, Domenico,Castaldo, Domenico
, p. 5156 - 5162 (2013)
The occurrence and distribution in Citrus genus plants of N-methylated derivatives of tryptamine and their 5-hydroxylated forms are reported. Tryptamine, N-methyltryptamine, N,N-dimethyltryptamine, N,N,N- trimethyltryptamine, 5-hydroxytryptamine (serotonin), 5-hydroxy-N- methyltryptamine, 5-hydroxy-N,N-dimethyltryptamine (bufotenine), and 5-hydroxy-N,N,N-trimethyltryptamine (bufotenidine) were quantitated by LC-ESI-MS/MS. Leaves of all citrus plants examined contained N,N,N-trimethyltryptamine, a compound that we first discovered in the bergamot plant. Interestingly, we also found out that all plants examined contained 5-hydroxy-N,N-dimethyltryptamine and 5-hydroxy-N,N,N-trimethyltryptamine, compounds never described so far in the Citrus genus. As N,N,N- trimethyltryptamine and 5-hydroxy-N,N,N-trimethyltryptamine possess nicotine-like activity by exerting their action on acetylcholine receptors, it is conceivable that both represent the arrival point of a biosynthetic pathway aimed to provide Citrus plants with chemical defense against aggressors. This hypothesis is supported by our finding that leaves and seeds, which are more frequently attacked by biotic agents, are the parts of the plant where the highest levels of those compounds were found.
