60671-89-8

Basic information

• Product Name: Benzene, 1-bromo-2-(2-nitrophenoxy)-
• CAS NO: 60671-89-8
• Molecular Formula: C12H8BrNO3
• Molecular Weight: 294.104
• Mol File: 60671-89-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-2-(2-nitrophenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-2-(2-nitrophenoxy)-(60671-89-8)
• EPA Substance Registry System: Benzene, 1-bromo-2-(2-nitrophenoxy)-(60671-89-8)

Safety Data

• Hazardous Substances Data: 60671-89-8(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 115750-83-9 (2-bromophenoxy)(tert-butyl)dimethylsilane 
• 88-73-3 2-Chloronitrobenzene 
• 89677-61-2 Methanesulfonic acid 2-bromo-phenyl ester 
• 95-56-7 2-hydroxybromobenzene 

Downstream Products

• 86607-81-0 4-nitrodibenzo[b,d]furan 
• 958244-60-5 (2-(2-bromophenoxy)phenyl)diphenylphosphine 
• 6192-43-4 1-(10H-phenoxazin-10-yl)ethan-1-one 
• 135-67-1 phenoxazine 
• 204847-21-2 N-(2-(2-bromophenoxy)phenyl)acetamide 
• 1316274-10-8 (+)-(S)-4-bromo-10-benzoyl-11-methyl-10,11-dihydrodibenzo[b,f][1,4]oxazepine 

Relevant articles and documents

Microwave assisted rapid synthesis of phenoxazines and benzopyridoxazines

A facile protocol for the synthesis of phenoxazines and benzopyridoxazines by Smiles rearrangement have been demonstrated in short reaction time under microwave irradiation. The control experiments suggest that a reaction proceeds through Smiles rearrangement followed SNAr ring closure by in situ cascade process. In our present work, both the electron donating and electron withdrawing groups were tolerant and provided a corresponding phenoxazine/benzopyridoxazine in good to moderate yields.

Csp2-Csp2 and Csp2-N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives

A novel, sequential, palladium-catalyzed, cross-coupling reaction using N-tosylhydrazone and bromonitrobenzene derivatives followed by reductive cyclization has been developed. This transformation providing an efficient route to unexpected N-arylindole derivatives involves, in a one-pot reaction, the formation of one Csp2-Csp2 bond and two Csp2-N bonds together with the cleavage of one Csp2-heteroatom bond. Evaluation of the biological activity led to the identification of compound 5a, which displays potent activity at nanomolar concentrations against human colon carcinoma cell line.

An efficient domino Sonogashira/double carbopalladation/C-H-activation reaction leading to fluorescent polycyclic aromatic hydrocarbons

A facile synthesis of fluorescent polycyclic aromatic hydrocarbons through a highly productive palladium-catalyzed fourfold domino Sonogashira/double carbopalladation/C-H-activation process was developed.