60680-42-4Relevant academic research and scientific papers
Silica gel catalyzed synthesis of quinoxialine 1,4-dioxides under solvent-free conditions using microwave irradiation
Sumiyoshi, Yusuke,Saito, Hiroaki,Miyairi, Shinichi,Takabatake, Tohru
scheme or table, p. 905 - 909 (2009/09/29)
We report on the simple and quick synthesis of quinoxaline 1,4-dioxides in solvent-free conditions under microwave irradiation. Heating of various benzofuroxans and β-ketoesters or 1,3-diketones adsorbed on silica gel in a microwave oven for two minutes affords diverse biologically attractive quinoxaline 1,4-dioxides in high to excellent yields. Silica gel functions not only as support using microwave but also as catalyst and dehydration reagent.
Method of Synthesizing Quinoxaline Derivative by Microwave Irradiation
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Page/Page column 3-4, (2009/03/07)
There is disclosed a method of synthesizing a quinoxaline derivative in which toxicity, corrosiveness and permeation are low and which is excellent in safety and which attains a reduced reaction time, a greatly improved yield and excellent economical effi
