60684-38-0Relevant academic research and scientific papers
Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents
Meng, Qingyi,Luo, Huibing,Liu, Yibin,Li, Wei,Zhang, Wen,Yao, Qizheng
, p. 2808 - 2810 (2009)
The low bioavailability of SQ109 in rats, resulting from first-pass effect in the liver, may be remedied by prodrug strategy. Based on esterase-sensitive carbamate prodrug strategy, a novel series of prodrugs of SQ109 has been reported. Bioavailability of
