60691-35-2

Upstream product

• 40807-61-2 4-hydroxy-4-phenylpiperidin 
• 3193-11-1 4-(2-chloro-ethyl)-1-isopropyl-3,3-diphenyl-pyrrolidin-2-one 

Relevant academic research and scientific papers

Heterocyclic antidiarrheal compositions & methods of use

1-R-4-(omega-substituted alkyl)-3,3-diphenyl-2-pyrrolidinones of the formula STR1 wherein R is hydrogen, lower alkyl, cyclohexyl or benzyl, R1 is hydrogen, chloro, bromo, fluoro, trifluoromethyl or lower alkoxy, R2 is hydrogen, chloro, bromo, or fluoro, A is hydroxy, lower-alkylcarbonyloxy or lower-alkoxycarbonyl and n is 1, 2 or 3 having analgetic and antidiarrheal activity are disclosed. The pharmaceutically acceptable acid addition salts of the bases are within the scope of the present invention.

Heterocyclic analgetic and antidiarrheal compounds

1-R-4-(omega-substituted alkyl)-3,3-diphenyl-2-pyrrolidinones of the formula STR1 wherein R is hydrogen, lower alkyl, cyclohexyl or benzyl, R1 is hydrogen, chloro, bromo, fluoro, trifluoromethyl or lower alkoxy, R2 is hydrogen, chloro, bromo, or fluoro, A is hydroxy, lower-alkylcarbonyloxy or lower-alkoxycarbonyl and n is 1, 2 or 3 having analgetic and antidiarrheal activity are disclosed. The pharmaceutically acceptable acid addition salts of the bases are within the scope of the present invention.