606937-79-5

Upstream product

• 6627-34-5 2,5-dichloro-4-nitroaniline 
• 20877-02-5 2-thio-N,N-dimethylbenzamide 
• 474432-18-3 2-(5-Amino-4-chloro-2-nitro-phenylthio)-N,N-dimethyl-benzamide 

Relevant academic research and scientific papers

Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters

This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invetion, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.

New PET imaging agent for the serotonin transporter: [18F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine)

A new F-18-labeled phenylthiophenyl derivative specific for imaging of serotonin transporters (SERT) in the brain by positron emission tomography (PET) is described. Fluorinated phenylthiophenyl derivative, ACF, 2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N