606937-97-7Relevant academic research and scientific papers
Total Synthesis of (±)-Isocembrene: A Tactic for both Diene Construction and Macrocycle Formation
Zhang, Fengzhi,Peng, Lizeng,Zhang, Tao,Mei, Tiansheng,Liu, Huawei,Li, Yulin
, p. 3761 - 3770 (2003)
The total synthesis of (±)-isocembrene 1, a naturally occurring cembrene diterpenoid, has been achieved via a unified, convergent and highly efficient strategy by imploying an intramolecular Stille sp2-sp 2 macrocyclization as the key step and it presents an ideal opportunity to extend the effectiveness of the tactic for both 1,3-diene construction and macrocycle formation.
Studies on novel macrocyclization methods of cembrane-type diterpenoids: A Stille cyclization approach to (±)-isocembrene
Peng, Lizeng,Zhang, Fengzhi,Mei, Tiansheng,Zhang, Tao,Li, Yulin
, p. 5921 - 5923 (2003)
An efficient total synthesis of (±)-isocembrene via an intramolecular Stille cross-coupling reaction is described. A novel strategy towards the 1,3-diene-based cembrane-type macrocyclic diterpenoids has been realized.
