60695-82-1

Basic information

• Product Name: 1-(3-benzoylphenyl)-1-bromoethane
• Synonyms: 1-(3-benzoylphenyl)-1-bromoethane
• CAS NO: 60695-82-1
• Molecular Weight: 289.172
• Mol File: 60695-82-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(3-benzoylphenyl)-1-bromoethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-benzoylphenyl)-1-bromoethane(60695-82-1)
• EPA Substance Registry System: 1-(3-benzoylphenyl)-1-bromoethane(60695-82-1)

Safety Data

• Hazardous Substances Data: 60695-82-1(Hazardous Substances Data)

Upstream product

• 66067-43-4 3-ethylbenzophenone 
• 22071-15-4 ketoprofen 

Downstream Products

• 60695-83-2 4-[1-(3-benzoylphenyl)ethyl]morpholine 
• 67173-18-6 3-(1-hydroxyethyl)benzophenone 

Relevant articles and documents

Decarboxylative Bromination of Sterically Hindered Carboxylic Acids with Hypervalent Iodine(III) Reagents

Sterically hindered three-dimensional (3D) alkyl halides are promising precursors for various reactions; however, they are difficult to synthesize via conventional reactions. We present an efficient and practical method for decarboxylative bromination of sterically hindered 3D aliphatic carboxylic acids using commercially available (diacetoxyiodo)benzene and potassium bromide, one of the most stable and cheapest bromine sources in nature. The present method features a metal-free/Br2-free system, mild reaction conditions, one-pot operation under air at room temperature, wide functional group compatibility, and gram-scale synthetic capability. This highly efficient reaction cleanly converts a broad range of carboxylic acids, the most inexpensive and readily available sources of highly strained/naturally occurring/drug-related scaffolds, into the corresponding alkyl bromides in good to high yields.

(Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid

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Method for preparing 3-ethylbenzophenone

The present invention provides a method for preparing 3-ethylbenzophenone in a high purity which comprises the steps of alkylating benzene with ethylene in the presence of an alkylating catalyst to obtain an alkylated product composed mainly of unreacted benzene, ethylbenzene, polyethylbenzenes and heavier substances; subjecting the alkylated product to rectification in order to recover therefrom a fraction which has a temperature range of boiling points within the range of 275° to 310° C. (in terms of atmospheric pressure); heating the recovered fraction together with a mixture of nitric acid and water; carrying out purification, if necessary; and performing distillation to recover therefrom 3-ethylbenzophenone represented by the formula (I): STR1