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Norcholic acid, an analogue of Cholic acid (C432600), is a novel bile acid with chemical properties that present as a light tan to pale yellow solid. It is derived from the modification of the structure of Cholic acid, a naturally occurring bile acid that plays a crucial role in the digestion and absorption of dietary fats.

60696-62-0

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60696-62-0 Usage

Uses

Used in Pharmaceutical Industry:
Norcholic acid is used as a pharmaceutical agent for its potential therapeutic applications. As a bile acid analogue, it may be involved in the regulation of cholesterol levels and the absorption of fat-soluble vitamins, making it a candidate for the treatment of various metabolic and digestive disorders.
Used in Drug Delivery Systems:
Norcholic acid can be utilized as a component in the development of drug delivery systems, particularly for targeted drug delivery. Its structural similarity to naturally occurring bile acids may allow for enhanced solubility and bioavailability of certain drugs, improving their efficacy and reducing side effects.
Used in Research and Development:
In the field of research and development, norcholic acid serves as a valuable compound for studying the structure-activity relationships of bile acids and their analogues. This knowledge can be applied to the design of new drugs and therapies targeting various diseases and conditions related to cholesterol metabolism and fat absorption.
Used in Cosmetics Industry:
Norcholic acid may also find applications in the cosmetics industry, where it could be used as an ingredient in products designed to improve skin health and appearance. Its potential effects on cholesterol regulation and fat absorption could be harnessed to create formulations that promote skin hydration, elasticity, and overall skin quality.

Check Digit Verification of cas no

The CAS Registry Mumber 60696-62-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,9 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 60696-62:
(7*6)+(6*0)+(5*6)+(4*9)+(3*6)+(2*6)+(1*2)=140
140 % 10 = 0
So 60696-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H38O5/c1-12(8-20(27)28)15-4-5-16-21-17(11-19(26)23(15,16)3)22(2)7-6-14(24)9-13(22)10-18(21)25/h12-19,21,24-26H,4-11H2,1-3H3,(H,27,28)/t12?,13-,14+,15+,16?,17?,18+,19-,21?,22-,23+/m0/s1

60696-62-0Relevant academic research and scientific papers

A convenient synthesis of dinorbile acids: Oxidative hydrolysis of norbile acid nitriles

Batta, Ashok K.,Datta, Subhash C.,Tint, G. Stephen,Alberts, David S.,Earnest, David L.,Salen, Gerald

, p. 780 - 784 (2007/10/03)

We report a convenient method for the synthesis of dinorbile acids (23,24-dinor-5β-cholan-22-oic acids, pregnane-20-carboxylic acids) in fair to good yields from norbile acid nitriles in one step by oxidative hydrolysis with oxygen in the presence of potassium-t-butoxide. The method results in stepwise overall removal of two carbon atoms in bile acid side chains in two steps. Dinorbile acids corresponding to several common bile acids have been prepared and their structures confirmed by spectroscopic methods. This simple method for synthesis of dinorbile acids may facilitate their study metabolically.

Bile acids for biological and chemical applications and processes for the production thereof

-

, (2008/06/13)

Novel bile acids according to the general formula STR1 wherein R1 represents a hydroxyl group, R2 and R3 both represent a hydrogen or a hydroxyl group, or R2 represents a hydroxyl group or a β hydroxyl group and

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