606966-44-3 Usage
Chemical structure
A synthetic fluorouracil derivative
Metabolism
Metabolized to 5-fluorouracil, a cytotoxic agent
Mechanism of action
Inhibits thymidylate synthase, resulting in the inhibition of DNA synthesis and tumor cell growth
Use
Commonly used in the treatment of various cancers, including breast, gastric, and colon cancer
Administration
Often administered in combination with other chemotherapeutic agents to enhance its effectiveness in killing cancer cells
Classification
Prodrug that is converted to its active form, 5-fluorouracil, in the body
Effectiveness
Widely used and effective treatment for a variety of cancers
Check Digit Verification of cas no
The CAS Registry Mumber 606966-44-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,6,9,6 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 606966-44:
(8*6)+(7*0)+(6*6)+(5*9)+(4*6)+(3*6)+(2*4)+(1*4)=183
183 % 10 = 3
So 606966-44-3 is a valid CAS Registry Number.
606966-44-3Relevant academic research and scientific papers
Cytosine analogues from substituted acetonitriles via Thorpe condensation
Barkin, Julia L.,Faust Jr., Marcus D.,Trenkle, William C.
, p. 3333 - 3335 (2007/10/03)
(Matrix presented) A Thorpe condensation is the key bond construction in a rapid and efficient synthesis of substituted cytosine derivatives from readily available starting materials.
