60698-06-8

Upstream product

• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 493-72-1 5-phenyl-cyclohexane-1,3-dione 

Downstream Products

• 132334-27-1 2-ethoxycarbonyl-3-methyl-4-oxo-6-phenyl-4,5,6,7-tetrahydrobenzofuran p-nitrophenylhydrazone 
• 863455-86-1 [4-(tert-butyldimethylsilanyloxy)-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran-2-yl]-(2,4-dimethoxyphenyl)methanone 
• 863455-87-2 (2,4-dimethoxyphenyl)-(4-hydroxy-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran-2-yl)methanone 
• 863455-85-0 4-(tert-butyldimethylsilanyloxy)-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid N-methoxy-N-methylamide 
• 863455-84-9 4-(tert-butyldimethylsilanyloxy)-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid ethyl ester 
• 863455-83-8 4-hydroxy-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid ethyl ester 
• 132334-28-2 1-Methyl-5-phenyl-5,10-dihydro-4H-3-oxa-10-aza-cyclopenta[a]fluorene-2-carboxylic acid ethyl ester 
• 132334-26-0 2-ethoxycarbonyl-3-methyl-4-oxo-6-phenyl-4,5,6,7-tetrahydrobenzofuran phenylhydrazone 

Relevant academic research and scientific papers

Synthesis and evaluation of 3-methyl-4-oxo-6-phenyl-4,5,6,7- tetrahydrobenzofuran-2-carboxylic acid ethyl ester derivatives as potent antitumor agents

For the construction of new combinatorial libraries, a lead compound was created by replacing the core structure of a hit compound discovered by screening for cytotoxic agents against a tumorigenic cell line. The newly designed compound maintained biologi