60703-46-0

Basic information

• Product Name: PYRIMIDINE, 2,4,6-TRICHLORO-5-METHOXY-
• Synonyms: PYRIMIDINE, 2,4,6-TRICHLORO-5-METHOXY-;2,4,6-trichloro-5-MethoxypyriMidine
• CAS NO: 60703-46-0
• Molecular Formula: C5H3Cl3N2O
• Molecular Weight: 213.45
• Mol File: 60703-46-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 67-68℃ (water, 50% ethanol )
• Boiling Point: 255.2°C at 760 mmHg
• Flash Point: 108.1°C
• Appearance: /
• Density: 1.572g/cm³
• Vapor Pressure: 0.0265mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -6.98±0.39(Predicted)
• CAS DataBase Reference: PYRIMIDINE, 2,4,6-TRICHLORO-5-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: PYRIMIDINE, 2,4,6-TRICHLORO-5-METHOXY-(60703-46-0)
• EPA Substance Registry System: PYRIMIDINE, 2,4,6-TRICHLORO-5-METHOXY-(60703-46-0)

Safety Data

• Hazardous Substances Data: 60703-46-0(Hazardous Substances Data)

Usage

General Description

Pyrimidine, 2,4,6-trichloro-5-methoxy- is a chemical compound with a molecular formula C6H3Cl3N2O. It is a derivative of pyrimidine with three chlorine atoms and one methoxy group attached to the pyrimidine ring. Pyrimidine, 2,4,6-trichloro-5-methoxy- is used in various chemical and pharmaceutical applications, including as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in research and development as a building block in the creation of new compounds with potential biological activities. However, due to its potentially hazardous nature, it should be handled and stored with proper safety precautions.

InChI:InChI=1/C5H3Cl3N2O/c1-11-2-3(6)9-5(8)10-4(2)7/h1H3

Upstream product

• 1382980-32-6 C₅H₅N₂O₄^(1-)*Na⁽¹⁺⁾ 
• 60703-43-7 6-hydroxy-5-methoxypyrimidine-2,4(1H,3H)-dione 
• 71720-62-2 6-hydroxy-5-methoxy-1H-pyrimidine-2,4-dione,sodium salt 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF

The present disclosure relates to inhibitors of one or more isoforms of RAS, such as inhibitors of one or more of KRAS, HRAS and NRAS, or mutants thereof, such as G12D, G12V, G13D or G12C mutants thereof. Therapeutic methods of treating conditions and dis

DIOXINO-AND OXAZIN-[2,3-D]PYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Dioxino-and oxazin-[2,3-d]pyrimidine PI3K inhibitor compounds of Formula I with anti-cancer activity, anti-in-flammatory activity, or immunoregulatory properties, and more specifically with PI3 kinase modulating or inhibitory activity are de-scribed. Methods are described for using the tricyclic PI3K inhibitor compounds of Formula I for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, organisms, or associated pathological conditions.

NOVEL PYRIMIDINE COMPOUNDS AS MTOR AND P13K INHIBITORS

The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.