60705-21-7Relevant articles and documents
Detours en route to a total synthesis of (+)-cassiol
Colombo, Maria I.,Zinczuk, Juan,Bohn, Maria L.,Ruveda, Edmundo A.
, p. 717 - 725 (2007/10/03)
A synthesis of the antiulcerogenic compound (+)-cassiol 1b has been achieved in 43% yield starting with lactol (S)-2 and sulfone 26. This short and efficient synthesis features the one-pot Julia olefination reaction of the sodium anion of (S)-2 with 26, through the key intermediate (-)-9. This synthesis has been developed as a result of exploratory experiments including different olefination reactions on 2. An attempt to synthesize the intermediate 9 by an intramolecular aldol condensation approach of the open chain precursor 4 is also described.
Stereoselective Synthesis of Trisporic Acids A and B, Their Methyl Esters, and Trisporols A and B, Hormones and Prohormones of Mucoraceous Fungi
White, James D.,Takabe, Kunihiko,Prisbylla, Michael P.
, p. 5233 - 5244 (2007/10/02)
Syntheses of (9E)- and (9Z)-trisporic acids A (1 and 4) and B (2 and 5) and the corresponding methyl esters (7, 10, 8, and 11, respectively) were accomplished via the Wittig reaction of lactol 52 with an appropriate phosphorane.The lactol was prepared by