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2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI), also known as CGS 19755, is a chemical compound characterized by a quinoxaline structure with a dihydro-6-hydroxy substitution. It functions as a specific antagonist at the glycine modulatory site of the NMDA receptor complex, which plays a crucial role in the regulation of neuronal excitability and synaptic transmission.

60729-17-1

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60729-17-1 Usage

Uses

Used in Pharmaceutical Industry:
2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI) is used as a neuroprotective agent for its potential to mitigate excitotoxicity and neuronal damage by blocking NMDA receptors. This property makes it a candidate for the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's, where excitotoxicity contributes to the progression of these conditions.
Used in Research Applications:
In the field of neuroscience, 2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI) is utilized as a research tool to study the role of NMDA receptors and glycine binding sites in various neurological processes and disorders. Its antagonistic action helps researchers understand the mechanisms of excitotoxicity and the potential therapeutic interventions for related conditions.
Used in Anticonvulsant Therapy:
2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI) is being investigated for its potential use in anticonvulsant therapy due to its ability to block NMDA receptors, which are implicated in the pathophysiology of seizures and epilepsy. By modulating the activity of these receptors, it may offer a novel approach to managing seizure disorders.
Further research is ongoing to explore the therapeutic applications of 2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI) and to assess its potential side effects, ensuring the safe and effective use of 2,3-Quinoxalinedione,1,4-dihydro-6-hydroxy-(9CI) in medical treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 60729-17-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,7,2 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60729-17:
(7*6)+(6*0)+(5*7)+(4*2)+(3*9)+(2*1)+(1*7)=121
121 % 10 = 1
So 60729-17-1 is a valid CAS Registry Number.

60729-17-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Hydroxy-1,4-dihydro-2,3-quinoxalinedione

1.2 Other means of identification

Product number -
Other names 6-Hydroxychinoxalin-2,3-dion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60729-17-1 SDS

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