60729-78-4

Basic information

• Product Name: N,N-Dimethyl-1-methyldodecylamine oxide
• Synonyms: N,N-Dimethyl-1-methyldodecylamine oxide
• CAS NO: 60729-78-4
• Molecular Formula: C15H33NO
• Molecular Weight: 243.42862
• Mol File: 60729-78-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N-Dimethyl-1-methyldodecylamine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethyl-1-methyldodecylamine oxide(60729-78-4)
• EPA Substance Registry System: N,N-Dimethyl-1-methyldodecylamine oxide(60729-78-4)

Safety Data

• Hazardous Substances Data: 60729-78-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H33NO/c1-5-6-7-8-9-10-11-12-13-14-15(2)16(3,4)17/h15H,5-14H2,1-4H3

Upstream product

• 60729-76-2 N-tridecane-2-yl-N,N-dimethylamine 

Relevant articles and documents

QSAR study on species differences in microsomal N-oxygenation of N,N-dimethylalkylamines

The metabolic N-oxygenation of nine long chain N,N-dimethylalkylamines and tri-n-butylamine has been studied using hepatic microsomal homogenates from mice, dogs and guinea-pigs. The relative oxidizability of amines (ROA) was correlated with structure, lipophilicity and nucleophilicity parameters of substrates and corresponding amine oxides formed in this biological reaction. The highest conversions of amines to N-oxides was found with male guinea-pig, followed by dog (male, female) and the lowest amount of amine oxides has been produced with male mice microsomal homogenates. The analyses were carried out by GLC and the results quantified using QSAR methodology. ROA is parabolically dependent upon structure and physicochemical properties of the substrates and products which was proved by the high statistical significance of the regression equations. The biological N-oxygenation of these amines is controlled by lipophilicity, stereochemistry and electronic effects.