607388-44-3

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 22977-45-3 methyl 7-chloro-3-oxoheptanoate 
• 20989-17-7 (2S)-2-phenylglycinol 
• 607388-37-4 [2-(4-chlorobutyl)-[1,3]dioxolan-2-yl]acetic acid methyl ester 

Downstream Products

• 607388-43-2 (2S)-[1-((S)-2-hydroxy-1-phenylethyl)piperidin-2-yl]acetic acid methyl ester 
• 171866-64-1 (2S)-methoxycarbonylmethylpiperidin 
• 131134-77-5 (S)-2-(methoxycarbonylmethyl)piperidine-1-carboxylic acid tert-butyl ester 
• 457603-49-5 8a-methoxycarbonylmethyl-3-(S)-phenylhexahydrooxazolo[3,2-a]pyridine 

Relevant academic research and scientific papers

Chiral heterocyclic β-enamino esters: Convenient synthesis and diastereoselective reduction

The preparation of chiral pyrrolidine and piperidine β-enamino esters starting from ω-halogeno β-keto esters, their diastereoselective reduction and the subsequent cleavage of the chiral auxiliary are described.