6074-63-1Relevant academic research and scientific papers
The first bismuth(III)-catalyzed guanylation of thioureas
Cunha, Silvio,Rodrigues Jr., Manoel T.
, p. 6955 - 6956 (2007/10/03)
This work describes the first catalytic bismuth-promoted synthesis of polysubstituted guanidines in good yields through the guanylation reaction of N-benzoyl or N-phenylthioureas with primary and secondary amines, but now employing equimolar amounts of ea
Bismuth nitrate pentahydrate: A new and environmentally benign reagent for guanidylation of N-benzoylthioureas
Cunha, Silvio,De Lima, Byanka R,De Souza, Aparecido R
, p. 49 - 52 (2007/10/03)
The bismuth nitrate-mediated guanidylation of N-benzoylthioureas was studied. This salt proved to be an effective guanylating reagent and allowed the obtention of N-benzoyl-guanidines in good yields. The methodology described is a promising alternative to the use of toxic HgCl2 in the synthesis of polysubstituted guanidines.
Study of N-benzoyl-activation in the HgCl2-promoted guanylation reaction of thioureas. Synthesis and structural analysis of N-benzoyl-guanidines
Cunha, Silvio,Costa, Maísa B,Napolitano, Hamilton B,Lariucci, Carlito,Vencato, Ivo
, p. 1671 - 1675 (2007/10/03)
In this work, it is demonstrated that the benzoyl group is an activating group for thioureas in the HgCl2-guanylation reaction. Thus N-benzoyl-thioureas containing electronically neutral and even electron-withdrawing or electron-releasing subst
