60742-72-5Relevant academic research and scientific papers
THE INFLUENCE OF α-ARYL ETHERS ON THE ASYMMETRIC REDUCTION OF CARBONYLS
Samuels, William D.,Nelson, David A.,Hallen, Richard T.
, p. 3091 - 3094 (2007/10/02)
The asymmetric reduction of α-aryl ethers 1 was found to be strongly influenced by the presence of ortho substituents on the aryl ring.Groups (methoxy or hydroxy) that chelate metal cations tend to stabilize a "locked" bicyclic 4 which, intermediate when
