607707-98-2

Upstream product

• 607707-89-1 (R)-(4-Benzyloxy-benzenesulfonylamino)-((4S,5R,4'S)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-acetic acid methyl ester 
• 607707-92-6 (R)-(4-Benzyloxy-benzenesulfonylamino)-[(4R,5R)-5-((S)-1,2-dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetic acid methyl ester 
• 607707-95-9 (R)-(4-Benzyloxy-benzenesulfonylamino)-[(4R,5R)-5-((S)-1-hydroxy-2-methanesulfonyloxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetic acid methyl ester 

Downstream Products

• 607708-03-2 (3aR,4R,7S,7aR)-5-(4-Cyclohexyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid hydroxyamide 
• 607707-99-3 (3aR,4R,7S,7aR)-5-(4-Cyclohexyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid methyl ester 
• 607708-02-1 (3aR,4R,7S,7aR)-5-(4-Benzyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid hydroxyamide 

Relevant academic research and scientific papers

Structure-activity relationships of azasugar-based MMP/ADAM inhibitors

In order to investigate structure-activity relationships of azasugar series toward metalloproteinases, we synthesized and evaluated several azasugar-based compounds. As a result, it was found that 4-phenoxybenzene derivative 3 having 2R,3R,4R,5S-configura