607723-87-5Relevant academic research and scientific papers
Process development and scale-up of PPAR α/γ Dual agonist lobeglitazone sulfate (CKD-501)
Lee, Hong Woo,Ahn, Joong Bok,Kang, Sung Kwon,Ahn, Soon Kil,Ha, Deok-Chan
, p. 190 - 199 (2012/12/26)
A scaleable synthetic route to the potent PPARα/γ dual agonistic agent, lobeglitazone (1), used for the treatment of type-2 diabetes was developed. The synthetic pathway comprises an effective five-step synthesis. This process involves a consecutive synth
Molecular design, synthesis, and hypoglycemic and hypolipidemic activities of novel pyrimidine derivatives having thiazolidinedione
Lee, Hong Woo,Bok, Young Kim,Joong, Bok Ahn,Sung, Kwon Kang,Lee, Jung Hwa,Jae, Soo Shin,Soon, Kil Ahn,Lee, Sang Joon,Seung, Soo Yoon
, p. 862 - 874 (2007/10/03)
We previously reported the synthesis and biological activity of novel substituted pyridines and purines having thiazolidinedione with hypoglycemic and hypolipidemic activities. We now report the synthesis and antidiabetic activity of novel substituted pyr
