607739-45-7

Upstream product

• 544671-79-6 N-[3,5-bis(trifluoromethyl)benzyl]-2-chloro-N-(3-hydroxypropyl)-4-iodo-3-pyridinecarboxamide 
• 544671-78-5 2-chloro-4-iodo-3-pyridinecarboxylic acid 
• 78607-36-0 2-chloro-3-iodopyridine 

Downstream Products

• 607739-49-1 5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-3,4,5,6-tetrahydro-2H-pyrido[4,3-b]-1,5-oxazocin-6-one 
• 607739-46-8 7-phenyl-3,4,5,6-tetrahydro-2H-pyrido[4,5-b]-1,5-oxazocine-6-one 
• 607739-55-9 5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-8-oxo-3,4,5,6-tetrahydro-2H-pyrido[4,3-b]-1,5-oxazocin-6-one 
• 607739-61-7 5-[3,5-bis(trifluoromethyl)benzyl]-9-chloro-7-(2-methylphenyl)-3,4,5,6-tetrahydro-2H-pyrido[4,3-b]-1,5-oxazocin-6-one 

Relevant academic research and scientific papers

Design, synthesis, and evaluation of novel 2-substituted-4-aryl-6,7,8,9- tetrahydro-5H-pyrimido[4,5-b][1,5]oxazocin-5-ones as NK1 antagonists

A series of novel bicyclic pyrimidine derivatives was prepared as part of a search for NK1 antagonist aimed at the treatment of urinary incontinence. Among them, 3g, a pyrimido[4,5-b][1,5]oxazocine derivative, bearing a 4-acetylpiperazinyl grou

Convenient synthesis of 7-aryl-3,4,5,6-tetrahydro-2H-pyrido[4,5-b]- and [2,3-b]-1,5-oxazocine-6-ones

A convenient and diversity-oriented method for synthesis of the novel 7-aryl-3,4,5,6-tetrahydro-2H-pyrido[4,5-b]-1,5-oxazocine-6-one skeleton 1 and the very rarely described 7-aryl-3,4,5,6-tetrahydro-2H-pyrido[2,3-b]-1,5- oxazocine-6-one skeleton 2, featu