607739-58-2Relevant academic research and scientific papers
Design and synthesis of novel 9-substituted-7-aryl-3,4,5,6-tetrahydro-2H- pyrido[4,3-b]- and [2,3-b]-1,5-oxazocin-6-ones as NK1 antagonists
Seto, Shigeki,Tanioka, Asao,Ikeda, Makoto,Izawa, Shigeru
, p. 1479 - 1484 (2007/10/03)
Novel 9-substituted-7-aryl-3,4,5,6-tetrahydro-2H-pyrido[4,3-b]- and [2,3-b]-1,5-oxazocin-6-ones were designed and prepared as part of a search for NK1 antagonists. Structure-activity relationship studies indicated that the conformational restri
