607744-33-2

Usage

Chemical Class

Phenyl-1,2,3,6-tetrahydropyridines

Usage

Synthetic compound used in pharmaceutical research and development

Functional Groups

Morpholine ring
Bromophenyl group
Ketone functional group

Structure

Valuable building block for creating new molecules with potential biological activity

Variability

Properties and uses may vary depending on specific application and context in research and development.

Upstream product

• 110-91-8 morpholine 
• 105515-33-1 3-(4-bromophenyl)prop-2-en-1-ol 
• 55394-81-5 3-(4-bromophenyl)propanoyl chloride 
• 1643-30-7 3-(4-bromophenyl)propionic acid 
• 92013-18-8 2-[(4-bromophenyl)methyl]propanedioic acid 
• 157134-36-6 dimethyl 2-(4-bromobenzyl)malonate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 136139-77-0 4-[(2E)-3-(4-bromophenyl)prop-2-enoyl]morpholine 

Downstream Products

• 607744-36-5 4-(3-(4-bromophenyl)propyl)morpholine 
• 607744-34-3 tert-butyl 4-[4-(3-morpholin-4-yl-3-oxopropyl)phenyl]piperazine-1-carboxylate 

Relevant academic research and scientific papers

Rhodium-catalyzed oxidative amidation of allylic alcohols and aldehydes: Effective conversion of amines and anilines into amides

The rhodium-catalyzed oxidative amidation of allylic alcohols and aldehydes is reported. In situ generated [(BINAP)Rh]BF4 catalyzes the one-pot isomerization/oxidative amidation of allylic alcohols or direct amidation of aldehydes using acetone or styrene as the hydrogen acceptor. The conditions are general, affording good to excellent yields with a wide array of amine and aniline nucleophiles, and chemoselective, other alcohols do not participate in the oxidation reaction. Utilization of biphasic conditions is critical, as they promote an equilibrium between the imine/enamine byproducts and the hemiaminal, which can undergo oxidation to the amide.

SUBSTITUTED BENZAMIDES AND THEIR USES

Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.

SUBSTITUTED BENZAMIDES AND THEIR USES

Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.

N-sulfonylurea apoptosis promoters

Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.