6078-06-4

Basic information

• Product Name: (R)-3-AMINO-BUTYRIC ACID METHYL ESTER
• Synonyms: (R)-3-AMINO-BUTYRIC ACID METHYL ESTER;Butanoic acid, 3-aMino-, Methyl ester;(R)-3-AMino-BbutyricacidMethylester;R-3-ABU-OME
• CAS NO: 6078-06-4
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.14634
• Mol File: 6078-06-4.mol
• Article Data: 38

Chemical Properties

• Boiling Point: 511°C at 760 mmHg
• Flash Point: 262.8°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 1.47E-10mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 8.71±0.10(Predicted)
• CAS DataBase Reference: (R)-3-AMINO-BUTYRIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-AMINO-BUTYRIC ACID METHYL ESTER(6078-06-4)
• EPA Substance Registry System: (R)-3-AMINO-BUTYRIC ACID METHYL ESTER(6078-06-4)

Safety Data

• Hazardous Substances Data: 6078-06-4(Hazardous Substances Data)

Usage

Uses

Methyl 3-aminobutanoate

InChI:InChI=1/C13H16N4O3/c1-8-15-16-9(2)17(8)14-7-10-5-11(19-3)13(18)12(6-10)20-4/h5-7,14H,1-4H3

Upstream product

• 67-56-1 methanol 
• 2835-82-7 3-aminobutyric acid 
• 14205-39-1 methyl 3-aminocrotonate 
• 105-45-3 acetoacetic acid methyl ester 
• 623-43-8 methyl crotonate 
• 3775-73-3 (R)-3-aminobutanoic acid 
• 1449430-60-7 C₂₀H₂₅NO₂ 
• 159877-47-1 methyl 3-(R)-[N-(tert-butoxycarbonyl)amino]-propanoate 
• 623-43-8 crotonic acid methyl ester 
• 678991-47-4 (-)-(3R)-methyl 3-(dibenzylamino)butanoate 
• 134430-97-0 methyl (3R,αR)-3-(N-benzyl-N-α-methylbenzylamino)butanoate 
• 64838-60-4 (3R,1'S)-3-<(1'-phenylethyl)amino>butanoic acid methyl ester 
• 53118-62-0 (R)-3-((S)-1-Phenyl-ethylamino)-butyric acid methyl ester 
• 3775-72-2 L-3-aminobutyric acid 

Downstream Products

• 2835-82-7 3-aminobutyric acid 
• 6168-83-8 (S)-3-Hydroxybutanoic Acid 
• 625-72-9 (R)-3-hydroxybutyric acid 
• 73786-48-8 1,2-dihydro-2-methyl-3-methoxycarbonyl-5,6-bis(tert-butylthio)pyridine 
• 5303-64-0 4-methyl-2-azetidinone 
• 106539-14-4 (S)-methyl 3-(tert-butyloxycarbonylamino)butyrate 
• 159877-47-1 methyl 3-(R)-[N-(tert-butoxycarbonyl)amino]-propanoate 
• 58610-41-6 (3S)-3-aminobutanoic acid hydrochloride 
• 163254-35-1 methyl 3-((tert-butoxycarbonyl)amino)butanoate 
• 1313618-76-6 C₁₆H₂₅N₃O₅S 
• 1313618-77-7 C₁₆H₂₅N₃O₅S 
• 142035-70-9 methyl (R)-3-(benzyloxycarbonylamino)-butanoate 
• 1425666-73-4 (R)-methyl 3-(ethoxycarbonylamino)butanoate 

Relevant articles and documents

MACROCYCLIC COMPOUND AS CDK INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE

The present invention relates to a macrocyclic compound as a CDK inhibitor, a preparation method therefor and the use thereof in medicine. Specifically, the present invention relates to a novel macrocyclic compound represented by a general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, the use thereof as a therapeutic agent, particularly as a CDK inhibitor, and the use thereof in treating cancers, inflammation, viral infections, cardiac hypertrophy or HIV, wherein each substituent of the general formula (I) is the same as that defined in the description.

Synthetic method of (R)-3- n-aminobutanol (by machine translation)

The invention belongs to, the field (R)- 3 - of pharmaceutical and chemical engineering, and particularly relates to a method for. preparing a product (R)- 3 - with good chemical purity, and optical, purity by, a, preparation method of a chiral drug midbody . (by machine translation)

Synthesis and evaluation of chiral β-amino acid-based low-molecular-weight organogelators possessing a methyl/trifluoromethyl side chain

The synthesis and gelation properties of chiral β-amino acid-based low-molecular-weight organogelators, possessing methyl/trifluoromethyl side chains, are reported. The structure of the side chain and chirality were found to be important parameters affecting the gelation ability. The pure enantiomer of the trifluoromethylated β-amino acid displayed good gelation properties due to the formation of fibrillar networks, driven by enhanced amide hydrogen bonding. An investigation of the effects of the alkyl chain length showed that longer alkyl chain improved the gelation ability, yet the same supramolecular structure was observed in all, as well as an odd-even effect in both the melting points and Tg values.