6078-17-7

Basic information

• Product Name: BERBAMINE DIHYDROCHLORIDE
• Synonyms: BERBENINE;BERBAMINE DIHYDROCHLORIDE;BERBAMINE HCL;BERBAMINE 2HCL;(4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-21,22,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-12-ol hydrochloride;6,6',7-Trimethoxy-2,2'-dimethylberbaman-12-ol dihydrochloride;Hydrochloride Berbamine;NH26773
• CAS NO: 6078-17-7
• Molecular Formula: C₃₇H₄₀N₂O₆*2ClH
• Molecular Weight: 665.65
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
• Mol File: 6078-17-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 250-253 °C(lit.)
• Boiling Point: 744.4 °C at 760 mmHg
• Flash Point: 404 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: ≥68 mg/mL in DMSO; ≥10.68 mg/mL in H2O; ≥4.57 mg/mL in EtOH
• CAS DataBase Reference: BERBAMINE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BERBAMINE DIHYDROCHLORIDE(6078-17-7)
• EPA Substance Registry System: BERBAMINE DIHYDROCHLORIDE(6078-17-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 6078-17-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 6078-17-7 differently. You can refer to the following data:
1. Reactant for:Preparation of and anti-leukemia active berbamine derivatives
2. (+)-Berbamine Dihydrochloride exerts anti-inflammatory effects through inhibition of NF-κB and MAPK signalling pathways.

Biological Activity

extracted from berberidis;store the product in sealed, cool and dry condition

Upstream product

• 478-61-5 berbamine 

Relevant articles and documents

Isoquinoline medicine and its preparation and use

The invention relates to an isoquinoline drug, and its preparation method and application. The molecular formula of the drug is C37H40N2O6.2HCl.nH2O, wherein n is 3 or 3.5. With good storage stability, the isoquinoline drug is suitable for application in preparation of medicines promoting proliferation of white blood cells, preventing white blood cell decrease after cancer radiotherapy and chemotherapy, resisting inflammation, resisting tuberculosis, resisting silicosis, resisting tumor, reducing blood pressure, resisting myocardial anoxia and ischemia, resisting arrhythmia, and treating or preventing other diseases.