60786-76-7Relevant academic research and scientific papers
Synthesis and evaluation of bifunctional chelating agents derived from bis(2-aminophenylthio)alkane for radioimaging with 99mTc
Chhikara, Bhupender S.,Kumar, Nitin,Tandon, Vibha,Mishra, Anil K.
, p. 4713 - 4720 (2005)
Novel bifunctional chelating agents bearing an aromatic rigid backbone have been synthesized and characterized on the basis of spectroscopic techniques. These macrocyclic multidentate chelating agents were conjugated with monoclonal antibody which forms stable complexes with 99mTc with high radiochemical purity.
KF-alumina immobilized in ionic liquids: A novel heterogeneous base for heterocyclization of alkylsulfanylphenylamines into 1,4-benzothiazine
Chhikara, Bhupender S.,Mishra, Anil K.,Tandon, Vibha
, p. 1057 - 1065 (2007/10/03)
A rapid and convenient synthetic methodology for the cyclocondensative transformation of various alkylsulfanylphenylamines with bromoacetyl bromide by supporting on KF-alumina in ionic liquids [bmim] [Br] and [bmim][BF 4] has been developed to obtain 3-oxo-1,4-benzothiazine in good yields. The product is easily obtained by extraction with ethyl acetate and concentrating under vacuum. Easy recovery of ionic liquid and use in consecutive reactions is also reported.
New chromogenic azothiacrown ethers - Synthesis and properties
Szczygelska-Tao,Biernat
, p. 931 - 936 (2007/10/03)
New chromogenic azocrown ethers possessing sulfur atoms and two azo- groups in the macrocycle are described. The synthesized macrocycles have been applied as ion carriers in ion-selective membrane electrodes. Their selectivity and sensitivity were studied
Synthetic ionophores part 19: Synthesis and ionophore character of 2- aminothiophenol based silver selective acyclic and cyclic receptors
Kumar, Subodh,Bhalla, Vandana,Singh, Harjit
, p. 5575 - 5586 (2007/10/03)
The phase transfer catalysed nucleophillic displacements of 1,5-dibromo- 3-oxapentane, 1,8-dibromo-3,6-dioxaoctane and 1,11-dibromo-3,6,9- trioxaundecane with thiophenol and 2-aminothiophenol provide respective acyclic receptors α,ω-bis(phenylthio/2-aminophenylthio)oxaalkanes (6-11). 1,8-Bis(2-aminophenylthio)-3,6-dioxaoctane (10) reacts with acetic anhydride and isophthaloyl chloride to provide acyclic (12) and macrocyclic (14) receptors, respectively. α,ω-(2-Aminophenylthio) oxaalkanes (9-11) undergo intermolecular cyclodehydro-chlorination with thiodiglycolyl dichloride and pyridine-2,6-dicarbonyl dichloride HCl to provide respective macrocycles 16- 18 and 20-22. The acyclic receptors 6-11 show strong complexation with Ag+ and Pb2+ with poor specificity towards Ag+. The conversion of amine units to amides in 12 significantly lowers the complexation but increases Ag+/M2+ selectivities. The organisation of ligating sites by converting acyclic receptor 12 to its cyclic analogs and the presence of additional ligating sites in cyclic receptors 16-18 and 20-22 not only restores the extraction abilities but also leads to high Ag+/M2+ selectivities. The macrocycles 17 and 21 respectively exhibit the highest transport (425) and extraction (564) Ag+/Pb2+ selectivities.
