608128-59-2Relevant academic research and scientific papers
Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors
Hanessian, Stephen,Sailes, Helen,Therrien, Eric
, p. 7047 - 7056 (2007/10/03)
Bicyclic sulfonamides were synthesized from 4-alkenyl N-alkenylsulfonyl L-prolines using a ring-closure metathesis reaction. Three types of bicyclic sulfonamides varying in the size of the second ring (5,5; 5,6; 5,7) were synthesized. A sulfonamide counte
