608131-99-3Relevant academic research and scientific papers
Substituted 6-amino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-ones: Synthesis, structure-activity relationships, and cytotoxic activity on selected human cancer cell lines
Li, Bin,Lyle, Michael P.A.,Chen, Genhui,Li, Jason,Hu, Kaiji,Tang, Liren,Alaoui-Jamali, Moulay A.,Webster, John
, p. 4601 - 4608 (2007)
An efficient synthesis and the cytotoxic activity of a series of substituted 6-amino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-ones 1a-q is described. The synthesis was accomplished in an expedient manner (seven-steps) from commercially available starting materials
NOVEL DITHIOLOPYRROLONES AND THEIR THERAPEUTICAL APPLICATIONS
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Page/Page column 15, (2008/06/13)
The present invention provides novel dithiolopyrrolone compounds and their salts, which promote production of white blood cells and are useful as prevention and treatments for microbial infections such as HIV infection and blood disorders such as neutropenia and other related diseases. The present invention also provides therapeutic compositions comprising particularly useful types of dithiolopyrrolones, the salts thereof, and methods and use in the manufacture of a medication for treatment of diseases.
