608136-52-3

Upstream product

• 608136-46-5 2,3-dihydro-2-(dimethylylidenmalonate)-5-phenyl-1H-1,4-benzodiazepine 
• 608136-48-7 (Z)-2,3-dihydro-2-[(methoxycarbonyl)methylen]-5-phenyl-1H-1,4-benzodiazepine 
• 608136-50-1 (E)-2,3-dihydro-2-[(methoxycarbonyl)methylen]-1-methyl-5-phenyl-1H-1,4-benzodiazepine 
• 2898-08-0 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 

Downstream Products

• 174311-64-9 2,3-dihydro-2-(2-hydroxyethyl)-1-methyl-5-phenyl-1H-1,4-benzodiazepine 
• 174311-47-8 2,3-dihydro-2-(2-chloroethyl)-1-methyl-5-phenyl-1H-1,4-benzodiazepine 
• 174311-51-4 2,3-dihydro-2-(2-aminoethyl)-1-methyl-5-phenyl-1H-1,4-benzodiazepine 
• 174311-49-0 2,3-dihydro-2-(2-phthalimidoethyl)-1-methyl-5-phenyl-1H-1,4-benzodiazepine 

Relevant academic research and scientific papers

Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as κ-opioid receptor agonists endowed with antinociceptive and antiamnesic activity

The synthesis and biological evaluation of a series of new derivatives of 2-substituted 5-phenyl-1,4-benzodiazepines, structurally related to tifluadom (5), are reported. Chemical and pharmacological studies on compounds 6 have been pursued with the aim o