60825-26-5

Usage

InChI:InChI=1/C8H6Cl3NO3/c1-14-6(13)3-15-8-5(10)2-4(9)7(11)12-8/h2H,3H2,1H3

Upstream product

• 2402-79-1 2,3,5,6-tetrachloropyridine 
• 6515-38-4 3,5,6-trichloropyridin-2 ol 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 64700-56-7 triclopyr butoxyethyl ester 
• 55335-06-3 triclopyr acid 

Relevant academic research and scientific papers

Synthesis and herbicidal activities of aryloxyacetic acid derivatives as HPPD inhibitors

A series of aryloxyacetic acid derivatives were designed and synthesized as 4-hydoxyphenylpyruvate dioxygenase (HPPD) inhibitors. Preliminary bioassay results reveal that these derivatives are promising Arabidopsis thaliana HPPD (AtHPPD) inhibitors, in particular compounds I12 (Ki = 0.011 μM) and I23 (Ki = 0.012 μM), which exhibit similar activities to that of mesotrione, a commercial HPPD herbicide (Ki = 0.013 μM). Furthermore, the newly synthesized compounds show significant greenhouse herbicidal activities against tested weeds at dosages of 150 g ai/ha. In particular, II4 exhibited high herbicidal activity for pre-emergence treatment that was slightly better than that of mesotrione. In addition, compound II4 was safe for weed control in maize fields at a rate of 150 g ai/ha, and was identified as the most potent candidate for a novel HPPD inhibitor herbicide. The compounds described herein may provide useful guidance for the design of new HPPD inhibiting herbicides and their modification.

Method for preparing sucrroxypyr-butoxyethyl ester by aqueous phase synthesis method (by machine translation)

1 (2, 2 - Trichlor 3-5-pyridyloxy) methyl acetate, ethylene glycol monobutyl ether and a catalyst, are added to a flask provided with a dryer, a condenser, a thermometer and a stirrer. (6 -) to obtain methyl sucralyl-butoxyethyl ester after the reaction process . sodium chloride, methyl acetate and dimethyl formamide are added to a flask provided with a dryer, a condenser, a thermometer and a stirrer to heat up, and the reaction system is dried, filtered, washed, stirred and dried to obtain -2 - (3, 2 - 3-pyridyloxy) methyl acetate; (iv) the reaction system is subjected to a reaction treatment step:2 - (. 5 6 -) The reaction system is filtered and dried to obtain methyl chloride, ethyl acetate and tert-butyl acetate. The method, provided by the invention, is simple to operate, environmentally friendly, raw materials are tetrachloropyridine, and the cost is lower. (by machine translation)

Triclopyr production method

The invention provides a triclopyr production method. Firstly, sodium trichloropyrindinol and methyl chloroacetate have etherification reaction in a polar solvent to generate a midbody trichloropyridine peroxyacetic acid methyl ester, and trichloropyridine peroxyacetic acid methyl ester is subjected to alkaline hydrolysis and acidification in an aqueous phase to obtain triclopyr. When etherification reaction is conducted, reaction temperature is low, conditions are mild, reaction time is shortened, post-processing is simple, and the yield is high. A dispersing agent and a phase transfer catalyst are used during alkaline hydrolysis and acidification, alkaline hydrolysis and acidification are conducted in the aqueous phase, the amount of three wastes is reduced, reaction conditions are mild, the yield is high, production cost is low, industrial production is facilitated, and the yield of two-step reaction can reach 94% or above.

Method of preparing alkyl halopyridinyloxyalkanoates

A novel method for the preparation of alkyl halopyridinyloxyalkanoate compounds is disclosed, which comprises reacting a halopyridine with an alkyl alpha-hydroxy alkanoate in the presence of an alkali metal carbonate promoter. The ester products prepared from this method are useful as herbicides.