60829-47-2Relevant academic research and scientific papers
USE OF SILVER(I) COMPLEXES AS ANTICANCER AGENTS
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Paragraph 0226, (2017/09/08)
The present invention relates to the use of silver(I) monophosphine complexes as Active Pharmaceutical Ingredients (API's), including anticancer agents, for the treatment, diagnosis and/or prevention of cancer. The present invention also relates to pharmaceutical compositions containing such complexes and further extends to a method of treating or diagnosing a subject/patient suffering from cancer.
USE OF SILVER (I) COMPLEXES AS ANTICANCER AGENTS
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Page/Page column 53; 60, (2013/06/27)
The present invention relates to the use of silver(l) monophosphine complexes as Active Pharmaceutical Ingredients (API's), including anticancer agents, for the treatment, diagnosis and/or prevention of cancer. The present invention also relates to pharmaceutical compositions containing such complexes and further extends to a method of treating or diagnosing a subject/patient suffering from cancer.
Lewis-Base Adducts of Group 11 Metal(I) Compounds. XXX. 3:1 Complexes of Triphenylphosphine with Silver(I) Halides
Engelhardt, Lutz M.,Healy, Peter C.,Patrick, Vincent A.,White, Allan H.
, p. 1873 - 1880 (2007/10/02)
3:1 adducts of triphenylphosphine, PPh3, with silver halides, AgX, have been characterized for chloride, bromide and iodide by single-crystal X-ray structure determinations, the chloride as its diacetone solvate.Crystals of the chloride, *2(CH3)2CO, are triclinic, P, a 13.654(4), b 14.059(4), c 13.970(4) Angstroem, α 84.82(2), β 87.71(2), γ 75.68(2) deg, Z 2; the structure was refined to a residual R of 0.061 for No = 2428 independent 'observed' reflections.Crystals of the bromide, , are trigonal, P3, a 19.366(6), c 10.787(6) Angstroem, Z 3, R was 0.054 for No = 2362.Crystals of the iodide, , are monoclinic, P21/n, a 18.993(8), b 13.807(4), c 17.78(8) Angstroem, β 96.11(4)deg, Z 4; R was 0.042 for No = 3691.Ag-Cl, Br, I respectively are 2.533(4), 2.671(6)-2.691(4) and 2.858((1) Angstroem, Ag-P for each of the three structures respectively lie in the ranges 2.558(5)-2.582(4), 2.528(3)-2.549(7) and 2.544(2)-2.780(3) Angstroem.
