608510-39-0Relevant articles and documents
Synthesis and binding selectivity of 7- and 15-decylbenzolactone-V8 for the C1 domains of protein kinase C isozymes
Nakagawa, Yu,Irie, Kazuhiro,Yamanaka, Nobuhiro,Ohigashi, Hajime,Tsuda, Ken-Ichiro
, p. 3015 - 3019 (2003)
Benzolactone-V8 (4) is a lactone analogue of the artificial tumor promoter benzolactam-V8 (1). To investigate the effect of hydrophobic substituents at positions 7 and 15 of 4 on binding selectivity for protein kinase C (PKC) isozymes, 7- and 15-decylbenz