608533-84-2

Upstream product

• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 1499-21-4 Diphenylphosphinic chloride 
• 2133-40-6 L-proline methyl ester monohydrochloride 

Downstream Products

• 1397283-02-1 (S)-N-((1-(diphenylphosphoryl)pyrrolidin-2-yl)methyl)-N-phenethyl-P,P-diphenylphosphinic amide 
• 1397283-07-6 C₁₇H₁₈NO₂P 
• 1397283-08-7 C₂₅H₂₉N₂OP 
• 608533-99-9 (S)-2-[(S)-1-(Diphenyl-phosphinoyl)-pyrrolidin-2-yl]-4-isopropyl-4,5-dihydro-oxazole 
• 62056-92-2 (S)-1-(Diphenyl-phosphinoyl)-pyrrolidine-2-carboxylic acid 

Relevant academic research and scientific papers

Readily available (S)-proline-derived organocatalysts for the Lewis acid-mediated Lewis base-catalyzed stereoselective aldol reactions of activated thioesters

A set of enantiomerically pure Lewis bases containing different diphenyl phosphinyl oxide groups were easily synthesized in a straightforward procedure by reaction of readily available proline-based scaffolds and phosphinoyl chlorides. The newly synthesiz

Two-fold amino acid-based chiral aminophosphine-oxazolines and use in asymmetric allylic alkylation

Chiral aminophosphine-oxazoline ligands derived from two different amino acids (tetrahydroisoquinoline carboxylic acid and proline) have been synthesized and examined as chiral auxiliaries in asymmetric allylic alkylation of three substrates. Stereoisomers 1a and 2a are providing the highest enantioselectivities (up to 94% ee) in the allylation of diphenylpropenyl acetate.