608535-10-0Relevant academic research and scientific papers
Efficient and convergent coupling route for the short-step synthesis of enantiopure 2α- and 2β-alkylated 1α,25-dihydroxy-19-norvitamin D3 analogues
Yoshida, Akihiro,Ono, Keiichiro,Suhara, Yoshitomo,Saito, Nozomi,Takayama, Hiroaki,Kittaka, Atsushi
, p. 1175 - 1179 (2007/10/03)
Novel efficient synthesis of several enantio-pure 2-alkylated 1α,25-dihydroxy-19-norvitamin D3 analogues through radical introduction of 2-alkyl chain and C5-C6 position coupling using Julia-type olefination as key steps w
Efficient synthesis of 2-modified 1α,25-dihydroxy-19-norvitamin D3 with Julia olefination: High potency in induction of differentiation on HL-60 cells
Ono, Keiichiro,Yoshida, Akihiro,Saito, Nozomi,Fujishima, Toshie,Honzawa, Shinobu,Suhara, Yoshitomo,Kishimoto, Seishi,Sugiura, Takayuki,Waku, Keizo,Takayama, Hiroaki,Kittaka, Atsushi
, p. 7407 - 7415 (2007/10/03)
Six novel 2-substituted analogues of 1α,25-dihydroxy-19-norvitamin D3, 6a,b-8a,b, were efficiently synthesized utilizing (-)-quinic acid as the A-ring precursor. The C2-modified A-rings were prepared as 4-alkylated (3R,5R)-3,5-dihydroxycyclohex
