608537-24-2Relevant academic research and scientific papers
Palladium-catalyzed synthesis of 1,2-dihydro-4(3H)-carbazolones. Formal total synthesis of murrayaquinone A
Scott, Tricia L.,S?derberg, Bj?rn C. G.
, p. 6323 - 6332 (2003)
Two sequential palladium-catalyzed reactions are the key steps in a novel synthetic route to 1,2-dihydro-4(3H)-carbazolones. The steps are an intermolecular Stille cross-coupling followed by a reductive N-heteroannulation. A formal total synthesis of murrayaquinone A, employing this sequence, is reported.
Metal-free synthesis of secondary arylamines: An aliphatic-to-aromatic transformation
Barros, M. Teresa,Dey, Suvendu S.,Maycock, Christopher D.
supporting information, p. 742 - 747 (2013/03/13)
An efficient method for the N-arylation of primary and some secondary amines using 2-halocyclohex-2-enones in an aliphatic-to-aromatic transformation in the presence of a substoichiometric amount of pTsOH has been developed. A series of arylamines have been synthesized from 2-halocyclohex-2-enones by in situ enamine formation followed by aromatization under environmentally friendly conditions using pTsOH. This metal-free, practical, relatively inexpensive protocol is of value in organic synthesis for industrial and academic applications. Copyright
