6087-16-7

Usage

Uses

Used in Pharmaceutical Industry:
2-fluoro-3-methylpentanoic acid is used as a building block for the synthesis of pharmaceutical compounds. Its unique structure and reactivity allow for the development of new drugs with specific properties and therapeutic effects.
Used in Chemical Industry:
2-fluoro-3-methylpentanoic acid is used as an intermediate in the synthesis of various chemical compounds. Its presence of a fluorine atom and a methyl group makes it a versatile compound for creating new molecules with specific chemical properties.
Used in Research and Development:
2-fluoro-3-methylpentanoic acid is used as a research compound to study its properties and potential applications. Further studies may be conducted to understand its behavior and explore its use in various fields, such as material science, catalysis, and environmental chemistry.

Upstream product

• 7309-45-7 ethyl 2-cyano-3-methylvalerate 
• 73-32-5 L-isoleucine 
• 73-32-5 L-isoleucine 
• 129265-04-9 1-Methoxy-1-(phenylthio)-2-fluoro-3-methyl-1-pentene 
• 319-78-8 isoleucine 
• 18283-07-3 2-Ethoxycarbonimidoyl-2-fluoro-3-methyl-pentanoic acid ethyl ester 

Downstream Products

• 132586-67-5 2-Fluoro-3-methyl-pentanoic acid 4-{5-[4-(2-fluoro-3-methyl-pentanoyloxy)-phenyl]-pyrimidin-2-yl}-phenyl ester 
• 136734-70-8 (2R,3S)-1-((2S,5S)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one 
• 136734-71-9 (2S,3S)-1-((2S,5S)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one 
• 136634-13-4 (2R,3S)-1-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one 
• 136734-69-5 (2S,3S)-1-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one 

Relevant academic research and scientific papers

An unusual conformation of α-haloamides due to cooperative binding with zincated porphyrins

CD and NMR spectroscopic evidence of cooperative binding between an α-halogen atom and a carboxamide group with a zinc porphyrin leads to an unprecedented conformation for the determination of the absolute stereochemistry of α-haloamides (α-halocarboxylic acids derivatized with 1,4-phenylenediamine) through the use of exciton-coupled circular dichroism (ECCD). With the use of chiral lactams, whose rotomeric contributions are minimized, both ECCD and NMR spectroscopy demonstrate that the porphyrin favors binding to the side of the sterically more demanding halogen atom as compared to the smaller hydrogen atom. In all, the data is strongly suggestive of an unusual conformation not observed before for α-chiral amides. A mnemonic for determining the absolute stereochemistry of α-halogenated carboxylic acids is provided.

Electrolytic Reactions of Fluoro Organic Compounds. 7. Anodic Methoxylation and Acetoxylation of 2,2,2-Trifluoroethyl Sulfides. Preparation of Highly Useful Trifluoromethylated Building Blocks

Anodic methoxylation and acetoxylation of 2,2,2-trifluoroethyl sulfides and the corresponding nonfluorinated sulfides were comparatively studied.It was found that a trifluoromethyl group remarkably promoted anodic substitution and methoxy and acetoxy groups were introduced adjacent to the trifluoromethyl group of the sulfides.Longer perfluoroalkyl groups also promoted these anodic substitutions.These products were shown to be highly useful building blocks fro the synthesis of fluoro organic compounds.

THE TRANSFORMATION OF α-AMINOACIDS INTO FLUOROACIDS

The reactions of some α-aminoacids with excess sodium nitrite in polyhydrogen fluoride-pyridine are described.