60901-08-8Relevant academic research and scientific papers
Iron-catalysed cross-coupling of halohydrins with aryl aluminium reagents: A protecting-group-free strategy attaining remarkable rate enhancement and diastereoinduction
Kawamura, Shintaro,Kawabata, Tatsuya,Ishizuka, Kentaro,Nakamura, Masaharu
supporting information; experimental part, p. 9376 - 9378 (2012/09/22)
Non-protected halohydrins are cross-coupled with aryl aluminium reagents to produce aryl alkanols in the presence of the iron-bisphosphine catalysts. Remarkable reaction rate enhancement and diastereoinduction are realized by the in situ generated aluminium alkoxides, offering a new method for the reactivity and selectivity control of the iron-catalysed cross-coupling reaction.
