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5-Phenyl-6H-1,3,4-thiadiazin-2-amine monohydrochloride, a chemical compound with the molecular formula C7H7N3S·HCl, is a white to off-white solid. It is a potent inhibitor of carbonic anhydrase, an enzyme that plays a crucial role in the regulation of fluid and ion balance in the body. 5-PHENYL-6H-1,3,4-THIADIAZIN-2-AMINE MONOHYDROCHLORIDE has demonstrated potential applications in the fields of medicine and chemistry, particularly in the development of pharmaceuticals and agrochemicals.

60912-78-9

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60912-78-9 Usage

Uses

Used in Pharmaceutical Industry:
5-Phenyl-6H-1,3,4-thiadiazin-2-amine monohydrochloride is used as a pharmaceutical intermediate for the development of drugs targeting carbonic anhydrase. Its ability to inhibit this enzyme makes it a promising candidate for the treatment of conditions such as glaucoma and other disorders related to fluid balance.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Phenyl-6H-1,3,4-thiadiazin-2-amine monohydrochloride is utilized as a key component in the synthesis of agrochemicals. Its role in these products is to help regulate the growth and development of plants, as well as manage pests and diseases.
Used in Cancer Research:
5-Phenyl-6H-1,3,4-thiadiazin-2-amine monohydrochloride has shown potential as an anti-cancer agent. It has been studied for its ability to inhibit the growth of certain cancer cell lines, making it a valuable compound in the ongoing search for novel cancer treatments.
Used in Drug Delivery Systems:
5-PHENYL-6H-1,3,4-THIADIAZIN-2-AMINE MONOHYDROCHLORIDE's potential applications extend to drug delivery systems, where it can be employed to improve the efficacy and targeted delivery of therapeutic agents, particularly in the treatment of glaucoma and other fluid balance-related disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 60912-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,9,1 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60912-78:
(7*6)+(6*0)+(5*9)+(4*1)+(3*2)+(2*7)+(1*8)=119
119 % 10 = 9
So 60912-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3S.ClH/c10-9-12-11-8(6-13-9)7-4-2-1-3-5-7;/h1-5H,6H2,(H2,10,12);1H

60912-78-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-phenyl-6H-1,3,4-thiadiazin-2-amine,hydrochloride

1.2 Other means of identification

Product number -
Other names 5-phenyl-6H-1,3,4-thiadiazin-2-amine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60912-78-9 SDS

60912-78-9Downstream Products

60912-78-9Relevant academic research and scientific papers

Silica phosphoric acid (SPA) as a highly active, reusable, heterogeneous catalyst for the synthesis of 2-amino/anilino-5-aryl-1,3,4-thiadiazine bromide derivatives

Rostamizadeh, Shahnaz,Amani, Ali Mohammad,Shadjou, Nasrin

experimental part, p. 238 - 244 (2012/02/16)

Silica phosphoric acid has been found to be an efficient catalyst for the synthesis of 2-amino/anilino-5-aryl-1,3,4-thiadiazine bromide derivatives from the reaction of thiosemicarbazide and α-bromoketones in acetonitrile at room temperature. The catalyst

A mild and highly efficient method for the synthesis of 5-aryl-(N-phenyl-)6H-1,3,4-thiadiazin-2-aminium salts using reusable heterogeneous catalysts

Rostamizadeh, Shahnaz,Shadjou, Nasrin,Amani, Ali M.,Aryan, Reza

experimental part, p. 1761 - 1764 (2009/05/31)

(Chemical Equation Presented) 5-Aryl-6H-1,3,4-thiadiazin-2-aminium and 5-aryl-N-phenyl-6H-1,3,4-thiadiazin-2-aminium salts have efficiently been synthesized from the reaction of thiosemicarbazide and α-haloketones in acetonitrile at room temperature using

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