609337-91-9Relevant academic research and scientific papers
SPIRO COMPOUNDS, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THE COMPOUNDS
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Page/Page column 24, (2010/02/13)
A spiro compound represented by the following formula (I) wherein R1 and R2 are the same or different and each is a hydrogen atom, a chlorine atom and the like, n is 1, 2 or 3, a bond containing a broken line is a single bond or a do
Discovery and preclinical characterization of (+)-3-[4-(1-piperidinoethoxy)phenyl]spiro[indene-1,1′-indane]-5, 5′-diol hydrochloride: A promising nonsteroidal estrogen receptor agonist for hot flush
Watanabe, Nobuhide,Ikeno, Akihisa,Minato, Hisao,Nakagawa, Hiroshi,Kohayakawa, Chie,Tsuji, Jun-Ichi
, p. 3961 - 3964 (2007/10/03)
In our studies of the development of a novel class of selective estrogen receptor modulators, (+)-3-[4-(1-piperidinoethoxy)phenyl]spiro[indene-1,1′ -indane]-5,5′-diol hydrochloride (1) was found to be an estrogen receptor ligand with beneficial effects in
